Carlos Frederico Martins Menck
From Laboratório de Reparo de DNA
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- | |Full Professor at the Dept. of Microbiology, of Institute of Biomedical Sciences, University of São Paulo. Graduated with major in Biology, and PhD in Biochemistry. His main research interest has been related to DNA repair, with studies not only in the cellular physiological aspects, but also from the point of view of evolution. | + | |Professor Titular do Depto. de Microbiologia, do Instituto de Ciências Biomédicas, Universidade de São Paulo. Graduado em Biologia e Doutorado em Bioquímica.|- |
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== Research Project == | == Research Project == | ||
- | His main research interests are the study of cellular DNA repair processes and their biological consequences (such as mutagenesis and cell death). Together with his group, he has developed systems related to gene therapy, and he has recently proposed the use of RNAi as a tool for the understanding the cell responses to genome aggression, in animal cells. celular). Considering the high levels of conservation of DNA repair genes in all living organisms, he also studies how these processes occor in plants and in bacteria. These studies also allow an evolutive approach to the projects of his group. Research (fazer link). | + | Seus interesses de pesquisa His main research interests are the study of cellular DNA repair processes and their biological consequences (such as mutagenesis and cell death). Together with his group, he has developed systems related to gene therapy, and he has recently proposed the use of RNAi as a tool for the understanding the cell responses to genome aggression, in animal cells. celular). Considering the high levels of conservation of DNA repair genes in all living organisms, he also studies how these processes occor in plants and in bacteria. These studies also allow an evolutive approach to the projects of his group. Research (fazer link). |
==Main Publications== | ==Main Publications== | ||
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05. Lima-Bessa, KM and Menck, CFM (2005) Skin cancer: lights on genome lesions. Current Biology, 15(2): R58-R61. | 05. Lima-Bessa, KM and Menck, CFM (2005) Skin cancer: lights on genome lesions. Current Biology, 15(2): R58-R61. | ||
- | 04. Marchetto MCN*, Muotri AR*, Burns DK, Friedberg EC and Menck CFM (2004) Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice. Proc. Natl. Acad. Sci. USA 101 (51): 17759-17764. Both authors have equally contributed. | + | 04. Marchetto MCN*, Muotri AR*, Burns DK, Friedberg EC and Menck CFM (2004) Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum mice. Proc. Natl. Acad. Sci. USA 101 (51): 17759-64. Both authors have equally contributed. |
03. Chiganças V, Sarasin, A and Menck, CF (2004) CPD-photolyase adenovirus-mediated gene transfer in normal and DNA repair deficient human cells. Journal Cell Science 117: 3579-3592. | 03. Chiganças V, Sarasin, A and Menck, CF (2004) CPD-photolyase adenovirus-mediated gene transfer in normal and DNA repair deficient human cells. Journal Cell Science 117: 3579-3592. |