Stephano Spanó Mello
From DNA Repair Lab
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Our goal is to study the influence of miRNA silencing in the response to ultraviolet (UV)-induced damage in fibroblast cell lines. Furthermore, we are also interested in the <i> in silico</i> determination of the mechanisms controlled by miRNAs, with a special interest in miRNAs involved in the control of repair mechanism. | Our goal is to study the influence of miRNA silencing in the response to ultraviolet (UV)-induced damage in fibroblast cell lines. Furthermore, we are also interested in the <i> in silico</i> determination of the mechanisms controlled by miRNAs, with a special interest in miRNAs involved in the control of repair mechanism. | ||
==Selected publications== | ==Selected publications== | ||
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+ | :Rassi DM, Junta CM, Fachin AL, Sandrin-Garcia P, Mello SS, Fernandes AP, Deghaide NN, Foss-Freitas MC, Foss MC, Sakamoto-Hojo ET, Passos GA, Donadi EA. Is HLA class II profile relevant for the study of large-scale differentially expressed genes in type 1 diabetes mellitus patients? Ann N Y Acad Sci. 2006 Oct;1079:305-9. <br> | ||
- | # Rassi DM, Junta CM, Fachin AL, Sandrin-Garcia P, Mello SS, Fernandes AP, Deghaide NN, Foss-Freitas MC, Foss MC, Sakamoto-Hojo ET, Passos GA, Donadi EA. Is HLA class II profile relevant for the study of large-scale differentially expressed genes in type 1 diabetes mellitus patients? Ann N Y Acad Sci. 2006 Oct;1079:305-9. <br> | + | Trevisan GL, Rassi DM, Baiao AM, Sandrin-Garcia P, Mello SS, Tamia-Ferreira MC, Junta CM, Fachin AL, Marques MM, Sakamoto-Hojo ET, Donadi EA, Passos GA. Using cDNA microarrays to identify human CD19(+) B cell gene products (ESTs) originated from systemic lupus erythematosus susceptibility loci. Autoimmun Rev. 2006 May;5(5):319-23. Epub 2006 Jan 6. Review.<br> |
- | # Trevisan GL, Rassi DM, Baiao AM, Sandrin-Garcia P, Mello SS, Tamia-Ferreira MC, Junta CM, Fachin AL, Marques MM, Sakamoto-Hojo ET, Donadi EA, Passos GA. Using cDNA microarrays to identify human CD19(+) B cell gene products (ESTs) originated from systemic lupus erythematosus susceptibility loci. Autoimmun Rev. 2006 May;5(5):319-23. Epub 2006 Jan 6. Review.<br> | + | Cardoso RS, Junta CM, Macedo C, Magalhaes DA, Silveira EL, Paula MO, Marques MM, Mello SS, Zarate-Blades CR, Nguyen C, Houlgatte R, Donadi EA, Sakamoto-Hojo ET, Passos GA. Hybridization signatures of gamma-irradiated murine fetal thymus organ culture (FTOC) reveal modulation of genes associated with T-cell receptor V(D)J recombination and DNA repair. Mol Immunol. 2006 Feb;43(5):464-72. Epub 2005 Apr 13. <br> |
- | #Cardoso RS, Junta CM, Macedo C, Magalhaes DA, Silveira EL, Paula MO, Marques MM, Mello SS, Zarate-Blades CR, Nguyen C, Houlgatte R, Donadi EA, Sakamoto-Hojo ET, Passos GA. Hybridization signatures of gamma-irradiated murine fetal thymus organ culture (FTOC) reveal modulation of genes associated with T-cell receptor V(D)J recombination and DNA repair. Mol Immunol. 2006 Feb;43(5):464-72. Epub 2005 Apr 13. <br> | + | Marques MM, Junta CM, Cardoso RS, Mello SS, Sakamoto-Hojo ET, Donadi EA, Passos GA. Changes in the gene expression profiling of the thymus in response to fibrosarcoma growth. Mol Cell Biochem. 2005 Aug;276(1-2):81-8.<br> |
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- | #Marques MM, Junta CM, Cardoso RS, Mello SS, Sakamoto-Hojo ET, Donadi EA, Passos GA. Changes in the gene expression profiling of the thymus in response to fibrosarcoma growth. Mol Cell Biochem. 2005 Aug;276(1-2):81-8.<br> | + | |
Magalhaes DA, Macedo C, Junta CM, Mello SS, Marques MM, Cardoso RS, Sakamoto-Hojo ET, Donadi EA, Passos GA. Hybridization signatures during thymus ontogeny reveals modulation of genes coding for T-cell signaling proteins. Mol Immunol. 2005 May;42(9):1043-8. Epub 2004 Nov 23. <br> | Magalhaes DA, Macedo C, Junta CM, Mello SS, Marques MM, Cardoso RS, Sakamoto-Hojo ET, Donadi EA, Passos GA. Hybridization signatures during thymus ontogeny reveals modulation of genes coding for T-cell signaling proteins. Mol Immunol. 2005 May;42(9):1043-8. Epub 2004 Nov 23. <br> | ||
- | #Pereira E, Tamia-Ferreira MC, Cardoso RS, Mello SS, Sakamoto-Hojo ET, Passos GA, Donadi EA. Immunosuppressive therapy modulates T lymphocyte gene expression in patients with systemic lupus erythematosus. Immunology. 2004 Sep;113(1):99-105. <br> | + | Pereira E, Tamia-Ferreira MC, Cardoso RS, Mello SS, Sakamoto-Hojo ET, Passos GA, Donadi EA. Immunosuppressive therapy modulates T lymphocyte gene expression in patients with systemic lupus erythematosus. Immunology. 2004 Sep;113(1):99-105. <br> |
*Sakamoto-Hojo ET, Mello SS, Pereira E, Fachin AL, Cardoso RS, Junta CM, Sandrin-Garcia P, Donadi EA, Passos GA. Gene expression profiles in human cells submitted to genotoxic stress. Mutat Res. 2003 Nov;544(2-3):403-13. | *Sakamoto-Hojo ET, Mello SS, Pereira E, Fachin AL, Cardoso RS, Junta CM, Sandrin-Garcia P, Donadi EA, Passos GA. Gene expression profiles in human cells submitted to genotoxic stress. Mutat Res. 2003 Nov;544(2-3):403-13. |