Raquel Paes da Rocha

From DNA Repair Lab

Graduated in Biological Sciences in Universidade de São Paulo – USP in 2005. Currently she is doing her PhD. program in the DNA repair Lab. Research area: DNA repair and relationships between genetic material integrity and cell cycle in Caulobacter crescentus.

Research abstract

C. crescentus is a model organism for cell cycle studies in prokaryotes. Its DNA repair mechanisms are, however, less studied and understood. C. crescentus genome has already been sequenced and several genes have been annotated as putative members of the genetic material integrity maintenance system. Even though, only few functional studies have been done. Therefore our objective is to bring more information about the DNA repair mechanisms in this organism. We also objective to analyze the implications of DNA damage to the singular cell cycle of this proteobacteria.

Publications

Galhardo, RS, Rocha, R. Marques, MV and Menck, CFM (2005) A SOS-regulated operon involved in damage-inducible mutagenesis in Caulobacter crescentus. Nucleic Acids Research, 33 (8): 2603-2614.

Rocha, RP, Paquola, ACM, Marques, MV, Menck, CFM and Galhardo, RS. (2008) Characterization of the SOS regulon of Caulobacter crescentus. J. Bacteriol., 190 (4): 1209-18.